Statistical methodology for recurrent events, with application to major trials in heart failure

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چکیده

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Statistical methodology for recurrent events, with application to major trials in heart failure

Composite outcomes are frequently adopted as primary endpoints in clinical trials as they consider fatal and non-fatal consequences of the disease under study and lead to higher event rates. Such analyses of time to first event are suboptimal for a chronic disease such as heart failure, characterised by recurrent hospitalisations, as information on repeats is ignored. We present a comparison of...

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ژورنال

عنوان ژورنال: Trials

سال: 2013

ISSN: 1745-6215

DOI: 10.1186/1745-6215-14-s1-p143